Span has reported two of the only three deaths from monkeypox outside of Africa in the most recent outbreak of the disease.

On Friday, Brazil confirmed its first monkeypox-related death.

Spain’s Ministry of Health said the country had 4,298 confirmed cases of monkeypox at the end of July.

Of these, just over 3% have been hospitalised and two have died, one on Friday and the second on Saturday.

In the whole of the European Union, there have been 11,000 cases since the beginning of the latest outbreak, according to the European Centre for Disease Prevention and Control.

Spain has the most reported cases, followed by Germany, France, the Netherlands and Portugal.

In the UK, there were 2,469 confirmed cases and 77 ‘highly probable’ cases of monkeypox on 28 July. The vast majority of cases were in England.