P &O Cruises will have half its fleet sailing again from Sunday when Ventura returns to the Canary Islands.
It will join Iona and Britannia in international waters.
P&O’s Azura will also resume sailing in December, joining Britannia for the Caribbean season.
The cruiseline’s President Paul Ludlow said: “Ventura’s international restart is the result of guest confidence in cruising and is the very latest stage of P&O Cruises sailing resumption as we work towards the return of our full fleet in spring 2022.
“Due to demand and the resounding endorsement of the first international holidays on Iona and Britannia we’ve opened up increased capacity to holiday with us.
“We’re proud to have four ships sailing internationally this year giving our guests a greater choice of where and when they travel with P&O Cruises for winter sun.”
Ventura will offer 12-night winter-sun holidays to Spain and Portugal this year followed by a 35-night holiday to the Caribbean, round-trip from Southampton, departing 3 January 3. A second 35-night holiday to the Caribbean and the US departs on 11 February.