Aer Lingus will launch a winter-only service to Las Vegas, which will connect with flights to Dublin from four UK airports.
The three-times-a-week service will start on 25 October, operating on Tuesdays, Thursdays and Saturdays.
The flights, operated by an Airbus A330-300, will continue until 29 April 2025.
Aer Lingus flights from London, Manchester, Glasgow and Edinburgh will connect with the Vegas service in Dublin, where passengers can clear US immigration, enabling them to arrive in the States like domestic passengers.